The Mitochondrial Epigenome: An Unexplored Avenue to Explain Unexplained Myopathies?

Mutations in either mitochondrial DNA (mtDNA) or nuclear genes that encode mitochondrial proteins may lead to dysfunctional mitochondria, giving rise to mitochondrial diseases. Some mitochondrial myopathies, however, present without a known underlying cause. Interestingly, methylation of mtDNA has b...

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Detalles Bibliográficos
Autores principales: Mposhi, Archibold, Liang, Lin, Mennega, Kevin P., Yildiz, Dilemin, Kampert, Crista, Hof, Ingrid H., Jellema, Pytrick G., de Koning, Tom J., Faber, Klaas Nico, Ruiters, Marcel H. J., Niezen-Koning, Klary E., Rots, Marianne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879787/
https://www.ncbi.nlm.nih.gov/pubmed/35216315
http://dx.doi.org/10.3390/ijms23042197

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