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Identification of a Common Pharmacophore for Binding to MMP2 and RGD Integrin: Towards a Multitarget Approach to Inhibit Cancer Angiogenesis and Metastasis

During tumor angiogenesis different growth factors, cytokines and other molecules interact closely with each other to facilitate tumor cell invasion and metastatic diffusion. The most intensively studied as molecular targets in anti-angiogenic therapies are vascular endothelial growth factor (VEGF)...

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Detalles Bibliográficos
Autores principales:	Baldini, Lorenzo, Lenci, Elena, Bianchini, Francesca, Trabocchi, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879803/ https://www.ncbi.nlm.nih.gov/pubmed/35209039 http://dx.doi.org/10.3390/molecules27041249

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