Factors Influencing the Crystallization-Onset Time of Metastable ASDs

In formulation development, amorphous solid dispersions (ASD) are considered to improve the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). However, the crystallization of APIs often limits long-term stability and thus the shelf life of ASDs. It has already been sho...

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Detalles Bibliográficos
Autores principales: Wolbert, Friederike, Fahrig, Ineke-Katharina, Gottschalk, Tobias, Luebbert, Christian, Thommes, Markus, Sadowski, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879851/
https://www.ncbi.nlm.nih.gov/pubmed/35214002
http://dx.doi.org/10.3390/pharmaceutics14020269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879851/
https://www.ncbi.nlm.nih.gov/pubmed/35214002
http://dx.doi.org/10.3390/pharmaceutics14020269

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