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Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures

We previously demonstrated that polybrominated diphenyl ethers (PBDEs) inhibit the growth of axons in primary rat hippocampal neurons. Here, we test the hypothesis that PBDE effects on axonal morphogenesis are mediated by thyroid hormone and/or reactive oxygen species (ROS)-dependent mechanisms. Axo...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Carty, Rhianna K., Bautista, Adrienne C., Hayakawa, Keri A., Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879960/
https://www.ncbi.nlm.nih.gov/pubmed/35202279
http://dx.doi.org/10.3390/toxics10020092

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