Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases

Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inh...

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Detalles Bibliográficos
Autores principales: Kofla-Dłubacz, Anna, Akutko, Katarzyna, Krzesiek, Elżbieta, Jamer, Tatiana, Braksator, Joanna, Grębska, Paula, Pytrus, Tomasz, Stawarski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879972/
https://www.ncbi.nlm.nih.gov/pubmed/35207271
http://dx.doi.org/10.3390/jcm11040994
Descripción
Sumario:Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inhibition of the TNF alpha pathway, group 12/23 cytokines, and lymphocyte migration is used in the treatment of severe or moderate ulcerative colitis and Crohn’s disease. Intracellular signal transduction by influencing the phosphorylation of SAT (signal transducer and activator of transcription) proteins remains in clinical trials.

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