Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases

Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inh...

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Autores principales: Kofla-Dłubacz, Anna, Akutko, Katarzyna, Krzesiek, Elżbieta, Jamer, Tatiana, Braksator, Joanna, Grębska, Paula, Pytrus, Tomasz, Stawarski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879972/
https://www.ncbi.nlm.nih.gov/pubmed/35207271
http://dx.doi.org/10.3390/jcm11040994
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author Kofla-Dłubacz, Anna
Akutko, Katarzyna
Krzesiek, Elżbieta
Jamer, Tatiana
Braksator, Joanna
Grębska, Paula
Pytrus, Tomasz
Stawarski, Andrzej
author_facet Kofla-Dłubacz, Anna
Akutko, Katarzyna
Krzesiek, Elżbieta
Jamer, Tatiana
Braksator, Joanna
Grębska, Paula
Pytrus, Tomasz
Stawarski, Andrzej
author_sort Kofla-Dłubacz, Anna
collection PubMed
description Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inhibition of the TNF alpha pathway, group 12/23 cytokines, and lymphocyte migration is used in the treatment of severe or moderate ulcerative colitis and Crohn’s disease. Intracellular signal transduction by influencing the phosphorylation of SAT (signal transducer and activator of transcription) proteins remains in clinical trials.
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spelling pubmed-88799722022-02-26 Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases Kofla-Dłubacz, Anna Akutko, Katarzyna Krzesiek, Elżbieta Jamer, Tatiana Braksator, Joanna Grębska, Paula Pytrus, Tomasz Stawarski, Andrzej J Clin Med Review Selective interference with the functioning of the immune system consisting of the selective blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the treatment of diseases resulting from dysregulation of the immune system, including inflammatory bowel disease. Inhibition of the TNF alpha pathway, group 12/23 cytokines, and lymphocyte migration is used in the treatment of severe or moderate ulcerative colitis and Crohn’s disease. Intracellular signal transduction by influencing the phosphorylation of SAT (signal transducer and activator of transcription) proteins remains in clinical trials. MDPI 2022-02-14 /pmc/articles/PMC8879972/ /pubmed/35207271 http://dx.doi.org/10.3390/jcm11040994 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kofla-Dłubacz, Anna
Akutko, Katarzyna
Krzesiek, Elżbieta
Jamer, Tatiana
Braksator, Joanna
Grębska, Paula
Pytrus, Tomasz
Stawarski, Andrzej
Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title_full Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title_fullStr Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title_full_unstemmed Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title_short Selective Forms of Therapy in the Treatment of Inflammatory Bowel Diseases
title_sort selective forms of therapy in the treatment of inflammatory bowel diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879972/
https://www.ncbi.nlm.nih.gov/pubmed/35207271
http://dx.doi.org/10.3390/jcm11040994
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