Cargando…
Kinetic and Molecular Docking Studies to Determine the Effect of Inhibitors on the Activity and Structure of Fused G6PD::6PGL Protein from Trichomonas vaginalis
Trichomoniasis is a sexually transmitted disease with a high incidence worldwide, affecting 270 million people. Despite the existence of a catalog of available drugs to combat this infection, their extensive use promotes the appearance of resistant Trichomonas vaginalis (T. vaginalis), and some side...
Autores principales: | Martínez-Rosas, Víctor, Hernández-Ochoa, Beatriz, Navarrete-Vázquez, Gabriel, Martínez-Conde, Carlos, Gómez-Chávez, Fernando, Morales-Luna, Laura, González-Valdez, Abigail, Arreguin-Espinosa, Roberto, Enríquez-Flores, Sergio, Pérez de la Cruz, Verónica, Aguayo-Ortiz, Rodrigo, Wong-Baeza, Carlos, Baeza-Ramírez, Isabel, Gómez-Manzo, Saúl |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880039/ https://www.ncbi.nlm.nih.gov/pubmed/35208965 http://dx.doi.org/10.3390/molecules27041174 |
Ejemplares similares
-
Characterizing the Fused TvG6PD::6PGL Protein from the Protozoan Trichomonas vaginalis, and Effects of the NADP(+) Molecule on Enzyme Stability
por: Morales-Luna, Laura, et al.
Publicado: (2020) -
Giardia lamblia G6PD::6PGL Fused Protein Inhibitors Decrease Trophozoite Viability: A New Alternative against Giardiasis
por: Morales-Luna, Laura, et al.
Publicado: (2022) -
Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis
por: Hernández-Ochoa, Beatriz, et al.
Publicado: (2022) -
Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia: Biochemical and In Silico Characterization of a New Druggable Target
por: Martínez-Rosas, Víctor, et al.
Publicado: (2023) -
Identification of the NADP(+) Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from Giardia lamblia
por: Morales-Luna, Laura, et al.
Publicado: (2019)