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Hydroxypropyl-β-cyclodextrin Enhances Oral Absorption of Silymarin Nanoparticles Prepared Using PureNano™ Continuous Crystallizer
The oral bioavailability of drugs is limited by factors such as poor membrane permeability, low solubility, and low dissolution rate. Silymarin (SLM) is a health-food active ingredient that is good for immunosuppression and tumor suppression. However, obtaining a good oral bioavailability is difficu...
Autores principales: | Onodera, Risako, Hayashi, Tomohiro, Motoyama, Keiichi, Tahara, Kohei, Takeuchi, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880042/ https://www.ncbi.nlm.nih.gov/pubmed/35214124 http://dx.doi.org/10.3390/pharmaceutics14020394 |
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