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Synthesis of (+)-(R)-Tiruchanduramine

The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.

Detalles Bibliográficos
Autores principales: Al-Taie, Zahraa S., Bartholomew, Barbara, Cartmell, Christopher, Froom, Richard T., Kerr, Russell G., Kraehenbuehl, Rolf, Murphy, Patrick J., Nash, Robert J., Penkova, Yana B., van Teijlingen, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880061/
https://www.ncbi.nlm.nih.gov/pubmed/35209136
http://dx.doi.org/10.3390/molecules27041338
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author Al-Taie, Zahraa S.
Bartholomew, Barbara
Cartmell, Christopher
Froom, Richard T.
Kerr, Russell G.
Kraehenbuehl, Rolf
Murphy, Patrick J.
Nash, Robert J.
Penkova, Yana B.
van Teijlingen, Alexander
author_facet Al-Taie, Zahraa S.
Bartholomew, Barbara
Cartmell, Christopher
Froom, Richard T.
Kerr, Russell G.
Kraehenbuehl, Rolf
Murphy, Patrick J.
Nash, Robert J.
Penkova, Yana B.
van Teijlingen, Alexander
author_sort Al-Taie, Zahraa S.
collection PubMed
description The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH.
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spelling pubmed-88800612022-02-26 Synthesis of (+)-(R)-Tiruchanduramine Al-Taie, Zahraa S. Bartholomew, Barbara Cartmell, Christopher Froom, Richard T. Kerr, Russell G. Kraehenbuehl, Rolf Murphy, Patrick J. Nash, Robert J. Penkova, Yana B. van Teijlingen, Alexander Molecules Article The absolute stereochemistry of the marine alkaloid (+)-(R)-tiruchanduramine was established via a convergent total synthesis in six steps and 15.5% overall yield from Fmoc-D-Dab(Boc)-OH. MDPI 2022-02-16 /pmc/articles/PMC8880061/ /pubmed/35209136 http://dx.doi.org/10.3390/molecules27041338 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Taie, Zahraa S.
Bartholomew, Barbara
Cartmell, Christopher
Froom, Richard T.
Kerr, Russell G.
Kraehenbuehl, Rolf
Murphy, Patrick J.
Nash, Robert J.
Penkova, Yana B.
van Teijlingen, Alexander
Synthesis of (+)-(R)-Tiruchanduramine
title Synthesis of (+)-(R)-Tiruchanduramine
title_full Synthesis of (+)-(R)-Tiruchanduramine
title_fullStr Synthesis of (+)-(R)-Tiruchanduramine
title_full_unstemmed Synthesis of (+)-(R)-Tiruchanduramine
title_short Synthesis of (+)-(R)-Tiruchanduramine
title_sort synthesis of (+)-(r)-tiruchanduramine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880061/
https://www.ncbi.nlm.nih.gov/pubmed/35209136
http://dx.doi.org/10.3390/molecules27041338
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