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Physicochemical Characterization and Pharmacological Evaluation of Novel Propofol Micelles with Low-Lipid and Low-Free Propofol
We developed safe and stable mixed polymeric micelles with low lipids and free propofol for intravenous administration, to overcome the biological barrier of the reticuloendothelial system (RES), reduce pain upon injection, and complications of marketed propofol formulation. The propofol-mixed micel...
Autores principales: | Chu, Yongchao, Sun, Tao, Xie, Zichen, Sun, Keyu, Jiang, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880186/ https://www.ncbi.nlm.nih.gov/pubmed/35214146 http://dx.doi.org/10.3390/pharmaceutics14020414 |
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