Cargando…

Palmitoylethanolamide Promotes White-to-Beige Conversion and Metabolic Reprogramming of Adipocytes: Contribution of PPAR-α

The potential role of brown and beige adipose tissue against obesity has been recognized. Browning, or beiging of white adipose tissue (WAT) is associated with the remodeling of adipocytes and the improvement of their metabolic and secretory functions. Here, palmitoylethanolamide (PEA) restore the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Annunziata, Chiara, Pirozzi, Claudio, Lama, Adriano, Senzacqua, Martina, Comella, Federica, Bordin, Antonella, Monnolo, Anna, Pelagalli, Alessandra, Ferrante, Maria Carmela, Mollica, Maria Pina, Iossa, Angelo, De Falco, Elena, Mattace Raso, Giuseppina, Cinti, Saverio, Giordano, Antonio, Meli, Rosaria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880285/ https://www.ncbi.nlm.nih.gov/pubmed/35214069 http://dx.doi.org/10.3390/pharmaceutics14020338

Ejemplares similares

Palmitoylethanolamide dampens neuroinflammation and anxiety-like behavior in obese mice
por: Lama, Adriano, et al.
Publicado: (2022)

Oral Bisphenol A Worsens Liver Immune-Metabolic and Mitochondrial Dysfunction Induced by High-Fat Diet in Adult Mice: Cross-Talk between Oxidative Stress and Inflammasome Pathway
por: Pirozzi, Claudio, et al.
Publicado: (2020)

Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism
por: Pirozzi, Claudio, et al.
Publicado: (2023)

Oxidative Stress and BPA Toxicity: An Antioxidant Approach for Male and Female Reproductive Dysfunction
por: Meli, Rosaria, et al.
Publicado: (2020)

Nutraceuticals: An integrative approach to starve Parkinson’s disease
por: Lama, Adriano, et al.
Publicado: (2020)

The Pressing Issue of Micro- and Nanoplastic Contamination: Profiling the Reproductive Alterations Mediated by Oxidative Stress
por: Ferrante, Maria Carmela, et al.
Publicado: (2022)

N-(1-carbamoyl-2-phenylethyl) butyramide reduces antibiotic-induced intestinal injury, innate immune activation and modulates microbiota composition
por: Lama, Adriano, et al.
Publicado: (2019)

Palmitoylethanolamide Treatment Reduces Blood Pressure in Spontaneously Hypertensive Rats: Involvement of Cytochrome P450-Derived Eicosanoids and Renin Angiotensin System
por: Mattace Raso, Giuseppina, et al.
Publicado: (2015)

High-Fat Diet Induces Neuroinflammation and Mitochondrial Impairment in Mice Cerebral Cortex and Synaptic Fraction
por: Cavaliere, Gina, et al.
Publicado: (2019)

Dual-Hit Model of Parkinson’s Disease: Impact of Dysbiosis on 6-Hydroxydopamine-Insulted Mice—Neuroprotective and Anti-Inflammatory Effects of Butyrate
por: Avagliano, Carmen, et al.
Publicado: (2022)

Subchronic Exposure to Polystyrene Microplastic Differently Affects Redox Balance in the Anterior and Posterior Intestine of Sparus aurata
por: Del Piano, Filomena, et al.
Publicado: (2023)

The Hepatic Mitochondrial Alterations Exacerbate Meta-Inflammation in Autism Spectrum Disorders
por: Trinchese, Giovanna, et al.
Publicado: (2022)

New Perspectives on the Potential Role of Aquaporins (AQPs) in the Physiology of Inflammation
por: Meli, Rosaria, et al.
Publicado: (2018)

PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis
por: Ye, Sihao, et al.
Publicado: (2020)

Interplay Between Peripheral and Central Inflammation in Autism Spectrum Disorders: Possible Nutritional and Therapeutic Strategies
por: Cristiano, Claudia, et al.
Publicado: (2018)

Extracorporeal shock waves alone or combined with raloxifene promote bone formation and suppress resorption in ovariectomized rats
por: Lama, Adriano, et al.
Publicado: (2017)

Selective activation of PPARα maintains thermogenic capacity of beige adipocytes
por: Egusa, Gentaro, et al.
Publicado: (2023)

Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet
por: Mattace Raso, Giuseppina, et al.
Publicado: (2013)

Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle
por: Cavaliere, Gina, et al.
Publicado: (2016)

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
por: Paterniti, Irene, et al.
Publicado: (2013)

Role of Innate Immune Response in Non-Alcoholic Fatty Liver Disease: Metabolic Complications and Therapeutic Tools
por: Meli, Rosaria, et al.
Publicado: (2014)

Decreased Metabolic Flexibility in Skeletal Muscle of Rat Fed with a High-Fat Diet Is Recovered by Individual CLA Isomer Supplementation via Converging Protective Mechanisms
por: Trinchese, Giovanna, et al.
Publicado: (2020)

Differential actions of PPAR-α and PPAR-β/δ on beige adipocyte formation: A study in the subcutaneous white adipose tissue of obese male mice
por: Rachid, Tamiris Lima, et al.
Publicado: (2018)

The Basal Pharmacology of Palmitoylethanolamide
por: Rankin, Linda, et al.
Publicado: (2020)

Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions
por: Yang, Nanfei, et al.
Publicado: (2022)

Micronized Palmitoylethanolamide Reduces the Symptoms of Neuropathic Pain in Diabetic Patients
por: Schifilliti, Chiara, et al.
Publicado: (2014)

Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical
por: Hesselink, Jan M Keppel
Publicado: (2013)

Delay of Morphine Tolerance by Palmitoylethanolamide
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2015)

Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics
por: Klusóczki, Ágnes, et al.
Publicado: (2019)

SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex
por: Shen, Huanming, et al.
Publicado: (2022)

Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes
por: Pisani, Didier F., et al.
Publicado: (2017)

Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism
por: Di Cesare Mannelli, L., et al.
Publicado: (2013)

Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action
por: Del Re, Alessandro, et al.
Publicado: (2022)

Calcium burns beige
por: Bunk, Jakub, et al.
Publicado: (2022)

Effect of ultramicronized-palmitoylethanolamide and co-micronized palmitoylethanolamide/polydatin on chronic pelvic pain and quality of life in endometriosis patients: An open-label pilot study
por: Stochino Loi, Emanuela, et al.
Publicado: (2019)

Engineering Human Beige Adipose Tissue
por: Gonzalez Porras, Maria A., et al.
Publicado: (2022)

Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation
por: Abe, Ichitaro, et al.
Publicado: (2022)

Synaptic Effects of Palmitoylethanolamide in Neurodegenerative Disorders
por: Assogna, Martina, et al.
Publicado: (2022)

El corsario beige : novela
por: Leduc, Renato
Publicado: (1940)

Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function
por: Berry, Daniel C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n04ffhc8ckf452cqe6eiba4smp