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Role of Cyclodextrins and Drug Solid State Properties on Flufenamic Acid Dissolution Performance from Tablets

Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence. Different FFA batches, obtained by different suppliers, showed different powder characteristics (particle size, shape and surface propert...

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Detalles Bibliográficos
Autores principales: Maestrelli, Francesca, Cirri, Marzia, De Luca, Enrico, Biagi, Diletta, Mura, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880332/
https://www.ncbi.nlm.nih.gov/pubmed/35214017
http://dx.doi.org/10.3390/pharmaceutics14020284