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Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads
Onchocerciasis and lymphatic filariasis are neglected tropical diseases caused by infection with filarial worms. Annual or biannual mass drug administration with microfilaricidal drugs that kill the microfilarial stages of the parasites has helped reduce infection rates and thus prevent transmission...
Autores principales: | Gunderson, Emma L., Bryant, Clifford, Bulman, Christina A., Fischer, Chelsea, Luo, Mona, Vogel, Ian, Lim, Kee-Chong, Jawahar, Shabnam, Tricoche, Nancy, Voronin, Denis, Corbo, Christopher, Ayiseh, Rene B., Manfo, Faustin P. T., Mbah, Glory E., Cho-Ngwa, Fidelis, Beerntsen, Brenda, Renslo, Adam R., Lustigman, Sara, Sakanari, Judy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880385/ https://www.ncbi.nlm.nih.gov/pubmed/35215301 http://dx.doi.org/10.3390/ph15020189 |
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