Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy

Chronic cardiac muscle inflammation and subsequent fibrotic tissue deposition are key features in Duchenne Muscular Dystrophy (DMD). The treatment of choice for delaying DMD progression both in skeletal and cardiac muscle are corticosteroids, supporting the notion that chronic inflammation in the he...

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Detalles Bibliográficos
Autores principales: Morroni, Jacopo, Schirone, Leonardo, Valenti, Valentina, Zwergel, Clemens, Riera, Carles Sánchez, Valente, Sergio, Vecchio, Daniele, Schiavon, Sonia, Ragno, Rino, Mai, Antonello, Sciarretta, Sebastiano, Lozanoska-Ochser, Biliana, Bouchè, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880527/
https://www.ncbi.nlm.nih.gov/pubmed/35216371
http://dx.doi.org/10.3390/ijms23042256

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