In-Silico Screening of Novel Synthesized Thienopyrimidines Targeting Fms Related Receptor Tyrosine Kinase-3 and Their In-Vitro Biological Evaluation

The present investigation describes the design strategy and synthesis of novel thienopyrimidine compounds in addition to their anticancer activity targeting tyrosine kinase FLT3 enzyme. The synthesized compounds were subjected to a cytotoxic study where compounds 9a and 9b showed the most potent cyt...

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Detalles Bibliográficos
Autores principales: Elmongy, Elshaymaa I., Altwaijry, Najla, Attallah, Nashwah G. M., AlKahtani, Manal Mubarak, Henidi, Hanan Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880588/
https://www.ncbi.nlm.nih.gov/pubmed/35215283
http://dx.doi.org/10.3390/ph15020170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880588/
https://www.ncbi.nlm.nih.gov/pubmed/35215283
http://dx.doi.org/10.3390/ph15020170

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