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Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study
Overweight and obesity have become a world-health public problem, mainly for developing countries. Both health conditions have a higher prevalence among women of childbearing age. Physiopathology, overweight and obesity are characterized by a chronic oxidative stress status, which has deleterious ef...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880599/ https://www.ncbi.nlm.nih.gov/pubmed/35215395 http://dx.doi.org/10.3390/nu14040746 |
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author | Lopez-Yañez Blanco, Arturo Díaz-López, Keyla M Vilchis-Gil, Jenny Diaz-Garcia, Hector Gomez-Lopez, Jacqueline Medina-Bravo, Patricia Granados-Riveron, Javier T Gallardo, Juan M Klünder-Klünder, Miguel Sánchez-Urbina, Rocío |
author_facet | Lopez-Yañez Blanco, Arturo Díaz-López, Keyla M Vilchis-Gil, Jenny Diaz-Garcia, Hector Gomez-Lopez, Jacqueline Medina-Bravo, Patricia Granados-Riveron, Javier T Gallardo, Juan M Klünder-Klünder, Miguel Sánchez-Urbina, Rocío |
author_sort | Lopez-Yañez Blanco, Arturo |
collection | PubMed |
description | Overweight and obesity have become a world-health public problem, mainly for developing countries. Both health conditions have a higher prevalence among women of childbearing age. Physiopathology, overweight and obesity are characterized by a chronic oxidative stress status, which has deleterious effects on mothers and children. Hence, we determine whether the qualities of diet during pregnancy and maternal pregestational body mass index (BMI) are associated with increased oxidative stress markers in mothers and newborns. Two hundred forty-two (242) mother-newborn pairs were classified according to their pregestational BMI. Information on food intake was collected using a food frequency questionnaire in the third trimester of pregnancy. Levels of Malondialdehyde (MDA) and Nitric Oxide (NO) were measured in plasma from mothers at the end of the third trimester of pregnancy and from cord blood at birth. MDA and NO levels in mother–newborn pairs with maternal pregestational overweight or obesity were higher than in mother–newborn pairs with pregestational normal weight. For women (and newborns) who had a higher intake of fruit and vegetables, the levels of NO and MDA were lower. Lastly, women with pregestational obesity had lower fruit and vegetable intake during pregnancy and higher levels of oxidative stress and in their newborns. |
format | Online Article Text |
id | pubmed-8880599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88805992022-02-26 Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study Lopez-Yañez Blanco, Arturo Díaz-López, Keyla M Vilchis-Gil, Jenny Diaz-Garcia, Hector Gomez-Lopez, Jacqueline Medina-Bravo, Patricia Granados-Riveron, Javier T Gallardo, Juan M Klünder-Klünder, Miguel Sánchez-Urbina, Rocío Nutrients Article Overweight and obesity have become a world-health public problem, mainly for developing countries. Both health conditions have a higher prevalence among women of childbearing age. Physiopathology, overweight and obesity are characterized by a chronic oxidative stress status, which has deleterious effects on mothers and children. Hence, we determine whether the qualities of diet during pregnancy and maternal pregestational body mass index (BMI) are associated with increased oxidative stress markers in mothers and newborns. Two hundred forty-two (242) mother-newborn pairs were classified according to their pregestational BMI. Information on food intake was collected using a food frequency questionnaire in the third trimester of pregnancy. Levels of Malondialdehyde (MDA) and Nitric Oxide (NO) were measured in plasma from mothers at the end of the third trimester of pregnancy and from cord blood at birth. MDA and NO levels in mother–newborn pairs with maternal pregestational overweight or obesity were higher than in mother–newborn pairs with pregestational normal weight. For women (and newborns) who had a higher intake of fruit and vegetables, the levels of NO and MDA were lower. Lastly, women with pregestational obesity had lower fruit and vegetable intake during pregnancy and higher levels of oxidative stress and in their newborns. MDPI 2022-02-10 /pmc/articles/PMC8880599/ /pubmed/35215395 http://dx.doi.org/10.3390/nu14040746 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lopez-Yañez Blanco, Arturo Díaz-López, Keyla M Vilchis-Gil, Jenny Diaz-Garcia, Hector Gomez-Lopez, Jacqueline Medina-Bravo, Patricia Granados-Riveron, Javier T Gallardo, Juan M Klünder-Klünder, Miguel Sánchez-Urbina, Rocío Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title | Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title_full | Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title_fullStr | Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title_full_unstemmed | Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title_short | Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study |
title_sort | diet and maternal obesity are associated with increased oxidative stress in newborns: a cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880599/ https://www.ncbi.nlm.nih.gov/pubmed/35215395 http://dx.doi.org/10.3390/nu14040746 |
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