The Tetrahydrofuran Motif in Polyketide Marine Drugs

Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An ove...

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Detalles Bibliográficos
Autores principales: Fernández-Peña, Laura, Díez-Poza, Carlos, González-Andrés, Paula, Barbero, Asunción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880653/
https://www.ncbi.nlm.nih.gov/pubmed/35200649
http://dx.doi.org/10.3390/md20020120
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author Fernández-Peña, Laura
Díez-Poza, Carlos
González-Andrés, Paula
Barbero, Asunción
author_facet Fernández-Peña, Laura
Díez-Poza, Carlos
González-Andrés, Paula
Barbero, Asunción
author_sort Fernández-Peña, Laura
collection PubMed
description Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An overview of the most important marine tetrahydrofuran polyketides, with a focused discussion on their isolation, structure determination, approaches to their total synthesis, and biological studies is provided.
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spelling pubmed-88806532022-02-26 The Tetrahydrofuran Motif in Polyketide Marine Drugs Fernández-Peña, Laura Díez-Poza, Carlos González-Andrés, Paula Barbero, Asunción Mar Drugs Review Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An overview of the most important marine tetrahydrofuran polyketides, with a focused discussion on their isolation, structure determination, approaches to their total synthesis, and biological studies is provided. MDPI 2022-02-03 /pmc/articles/PMC8880653/ /pubmed/35200649 http://dx.doi.org/10.3390/md20020120 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Fernández-Peña, Laura
Díez-Poza, Carlos
González-Andrés, Paula
Barbero, Asunción
The Tetrahydrofuran Motif in Polyketide Marine Drugs
title The Tetrahydrofuran Motif in Polyketide Marine Drugs
title_full The Tetrahydrofuran Motif in Polyketide Marine Drugs
title_fullStr The Tetrahydrofuran Motif in Polyketide Marine Drugs
title_full_unstemmed The Tetrahydrofuran Motif in Polyketide Marine Drugs
title_short The Tetrahydrofuran Motif in Polyketide Marine Drugs
title_sort tetrahydrofuran motif in polyketide marine drugs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880653/
https://www.ncbi.nlm.nih.gov/pubmed/35200649
http://dx.doi.org/10.3390/md20020120
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