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Epigenetic scores for the circulating proteome as tools for disease prediction
Protein biomarkers have been identified across many age-related morbidities. However, characterising epigenetic influences could further inform disease predictions. Here, we leverage epigenome-wide data to study links between the DNA methylation (DNAm) signatures of the circulating proteome and inci...
Autores principales: | Gadd, Danni A, Hillary, Robert F, McCartney, Daniel L, Zaghlool, Shaza B, Stevenson, Anna J, Cheng, Yipeng, Fawns-Ritchie, Chloe, Nangle, Cliff, Campbell, Archie, Flaig, Robin, Harris, Sarah E, Walker, Rosie M, Shi, Liu, Tucker-Drob, Elliot M, Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Graumann, Johannes, McRae, Allan F, Deary, Ian J, Porteous, David J, Hayward, Caroline, Visscher, Peter M, Cox, Simon R, Evans, Kathryn L, McIntosh, Andrew M, Suhre, Karsten, Marioni, Riccardo E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880990/ https://www.ncbi.nlm.nih.gov/pubmed/35023833 http://dx.doi.org/10.7554/eLife.71802 |
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