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Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies

The rapid (<1 ms) transport of biological material to and from the cell nucleus is regulated by the nuclear pore complex (NPC). At the core of the NPC is a permeability barrier consisting of intrinsically disordered phenylalanine-glycine nucleoporins (FG Nups). Various types of nuclear transport...

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Detalles Bibliográficos
Autores principales: Davis, Luke K, Ford, Ian J, Hoogenboom, Bart W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880993/
https://www.ncbi.nlm.nih.gov/pubmed/35098921
http://dx.doi.org/10.7554/eLife.72627