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Real-Time RT-PCR Allelic Discrimination Assay for Detection of N501Y Mutation in the Spike Protein of SARS-CoV-2 Associated with B.1.1.7 Variant of Concern

The N501Y amino acid mutation caused by a single point substitution A23063T in the spike gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is possessed by three variants of concern (VOCs), B.1.1.7, B.1.351, and P.1. A rapid screening tool using this mutation is important for surve...

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Detalles Bibliográficos
Autores principales: Abdulnoor, Mariana, Eshaghi, AliReza, Perusini, Stephen J., Broukhanski, George, Corbeil, Antoine, Cronin, Kirby, Fittipaldi, Nahuel, Forbes, Jessica D., Guthrie, Jennifer L., Kus, Julianne V., Li, Ye, Majury, Anna, Mallo, Gustavo V., Mazzulli, Tony, Melano, Roberto G., Olsha, Romy, Sullivan, Ashleigh, Tran, Vanessa, Patel, Samir N., Allen, Vanessa G., Gubbay, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881086/
https://www.ncbi.nlm.nih.gov/pubmed/35170989
http://dx.doi.org/10.1128/spectrum.00681-21