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Real-Time RT-PCR Allelic Discrimination Assay for Detection of N501Y Mutation in the Spike Protein of SARS-CoV-2 Associated with B.1.1.7 Variant of Concern
The N501Y amino acid mutation caused by a single point substitution A23063T in the spike gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is possessed by three variants of concern (VOCs), B.1.1.7, B.1.351, and P.1. A rapid screening tool using this mutation is important for surve...
Autores principales: | Abdulnoor, Mariana, Eshaghi, AliReza, Perusini, Stephen J., Broukhanski, George, Corbeil, Antoine, Cronin, Kirby, Fittipaldi, Nahuel, Forbes, Jessica D., Guthrie, Jennifer L., Kus, Julianne V., Li, Ye, Majury, Anna, Mallo, Gustavo V., Mazzulli, Tony, Melano, Roberto G., Olsha, Romy, Sullivan, Ashleigh, Tran, Vanessa, Patel, Samir N., Allen, Vanessa G., Gubbay, Jonathan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881086/ https://www.ncbi.nlm.nih.gov/pubmed/35170989 http://dx.doi.org/10.1128/spectrum.00681-21 |
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