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BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study
METHODS: 146 adult liver transplant recipients were included. Univariate and multivariate analyses were used to determine the independent predictors of survival at 3 months, 1 year, and 5 years. The receiver operating characteristic (ROC) curve for the BAR score was plotted, and the area under the R...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881181/ https://www.ncbi.nlm.nih.gov/pubmed/35223683 http://dx.doi.org/10.1155/2022/2877859 |
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author | Zakareya, Talaat Taha, Mohammad Elzohry, Hassan Darwiesh, Ehab Aglan, Reda Elhelbawy, Mostafa Zakaria, Hazem Deif, Mohamed Abbasy, Mohamed |
author_facet | Zakareya, Talaat Taha, Mohammad Elzohry, Hassan Darwiesh, Ehab Aglan, Reda Elhelbawy, Mostafa Zakaria, Hazem Deif, Mohamed Abbasy, Mohamed |
author_sort | Zakareya, Talaat |
collection | PubMed |
description | METHODS: 146 adult liver transplant recipients were included. Univariate and multivariate analyses were used to determine the independent predictors of survival at 3 months, 1 year, and 5 years. The receiver operating characteristic (ROC) curve for the BAR score was plotted, and the area under the ROC curve (AUROC) was calculated. Kaplan–Meier curve and log-rank test were used to compare survival above and below the best cutoff values. RESULTS: The mean age was 52.45 ± 8.54 years, and 59.6% were males. The survival rates were 89, 78.8, and 72% at 3 months, 1 year, and 5 years, respectively. The BAR score demonstrated a clinically significant value in the prediction of 3-month (AUROC = 0.89), 1-year (AUROC = 0.76), and 5-year survival (AUROC = 0.71). Among the investigated factors associated with survival, BAR score <10 points was the only independent predictor of 3-month (OR 7.34, p < 0.0001), 1-year (OR 3.37, p=0.001), and 5-year survival (OR 2.83, p=0.044). CONCLUSIONS: BAR is a simple and easily applicable scoring system that could significantly predict short- and long-term survival after LDLT. A large multicenter study is warranted to validate our results in the Egyptian population. |
format | Online Article Text |
id | pubmed-8881181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-88811812022-02-26 BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study Zakareya, Talaat Taha, Mohammad Elzohry, Hassan Darwiesh, Ehab Aglan, Reda Elhelbawy, Mostafa Zakaria, Hazem Deif, Mohamed Abbasy, Mohamed Can J Gastroenterol Hepatol Research Article METHODS: 146 adult liver transplant recipients were included. Univariate and multivariate analyses were used to determine the independent predictors of survival at 3 months, 1 year, and 5 years. The receiver operating characteristic (ROC) curve for the BAR score was plotted, and the area under the ROC curve (AUROC) was calculated. Kaplan–Meier curve and log-rank test were used to compare survival above and below the best cutoff values. RESULTS: The mean age was 52.45 ± 8.54 years, and 59.6% were males. The survival rates were 89, 78.8, and 72% at 3 months, 1 year, and 5 years, respectively. The BAR score demonstrated a clinically significant value in the prediction of 3-month (AUROC = 0.89), 1-year (AUROC = 0.76), and 5-year survival (AUROC = 0.71). Among the investigated factors associated with survival, BAR score <10 points was the only independent predictor of 3-month (OR 7.34, p < 0.0001), 1-year (OR 3.37, p=0.001), and 5-year survival (OR 2.83, p=0.044). CONCLUSIONS: BAR is a simple and easily applicable scoring system that could significantly predict short- and long-term survival after LDLT. A large multicenter study is warranted to validate our results in the Egyptian population. Hindawi 2022-02-18 /pmc/articles/PMC8881181/ /pubmed/35223683 http://dx.doi.org/10.1155/2022/2877859 Text en Copyright © 2022 Talaat Zakareya et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zakareya, Talaat Taha, Mohammad Elzohry, Hassan Darwiesh, Ehab Aglan, Reda Elhelbawy, Mostafa Zakaria, Hazem Deif, Mohamed Abbasy, Mohamed BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title | BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title_full | BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title_fullStr | BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title_full_unstemmed | BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title_short | BAR Score Performance in Predicting Survival after Living Donor Liver Transplantation: A Single-Center Retrospective Study |
title_sort | bar score performance in predicting survival after living donor liver transplantation: a single-center retrospective study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881181/ https://www.ncbi.nlm.nih.gov/pubmed/35223683 http://dx.doi.org/10.1155/2022/2877859 |
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