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The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies
BACKGROUND: There is an ongoing global effort to design, manufacture, and clinically assess vaccines against SARS-CoV-2. Over the course of the ongoing pandemic a number of new SARS-CoV-2 virus isolates or variants of concern (VoC) have been identified containing mutations in key proteins. METHODS:...
Autores principales: | Spencer, Alexandra J, Morris, Susan, Ulaszewska, Marta, Powers, Claire, Kailath, Reshma, Bissett, Cameron, Truby, Adam, Thakur, Nazia, Newman, Joseph, Allen, Elizabeth R, Rudiansyah, Indra, Liu, Chang, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Davies, Hannah, Donnellan, Francesca R, Pulido, David, Peacock, Thomas P., Barclay, Wendy S., Bright, Helen, Ren, Kuishu, Screaton, Gavin, McTamney, Patrick, Bailey, Dalan, Gilbert, Sarah C, Lambe, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881183/ https://www.ncbi.nlm.nih.gov/pubmed/35228013 http://dx.doi.org/10.1016/j.ebiom.2022.103902 |
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