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Selection of Aspergillus fumigatus isolates carrying the G448S substitution in CYP51A gene after long-term treatment with voriconazole in an immunocompromised patient

We present a case of a 55-year-old man with a heart transplant who acquired Invasive Aspergillosis by Aspergillus fumigatus with the focus in the kidney. During about two years of antifungal treatment, most of the time with voriconazole, it was possible to obtain nine isolates of A. fumigatus, with...

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Detalles Bibliográficos
Autores principales: Pontes, Laís, Gualtieri Beraquet, Caio Augusto, Arai, Teppei, Watanabe, Akira, Moretti, Maria Luiza, Schreiber, Angelica Zaninelli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881195/
https://www.ncbi.nlm.nih.gov/pubmed/35242508
http://dx.doi.org/10.1016/j.mmcr.2022.02.002

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