A behavioral weight-loss intervention, but not metformin, decreases a marker of gut barrier permeability: Results from the SPIRIT randomized trial

BACKGROUND/OBJECTIVES: Lipopolysaccharide-binding protein (LBP), a biomarker of gut barrier permeability to lipopolysaccharides, is higher in adults with obesity and type 2 diabetes. Behavioral weight loss and metformin have distinct effects on the gut microbiome, but their impact on gut permeabilit...

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Detalles Bibliográficos
Autores principales: Tilves, Curtis, Yeh, Hsin-Chieh, Maruthur, Nisa, Juraschek, Stephen P., Miller, Edgar, Appel, Lawrence J., Mueller, Noel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881332/
https://www.ncbi.nlm.nih.gov/pubmed/34987204
http://dx.doi.org/10.1038/s41366-021-01039-2

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