The efficacy of duloxetine depends on spinal cholinergic plasticity in neuropathic pain model rats

Antidepressants, such as duloxetine, are widely used to treat chronic pain, including neuropathic pain; however, their efficacy is unsatisfactory. In our previous studies, we showed that in a spinal nerve ligation (SNL) rat model, the descending noradrenergic inhibitory system, which involves in the...

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Detalles Bibliográficos
Autores principales: Kato, Daiki, Suto, Takashi, Obata, Hideaki, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881419/
https://www.ncbi.nlm.nih.gov/pubmed/35243478
http://dx.doi.org/10.1016/j.ibneur.2022.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881419/
https://www.ncbi.nlm.nih.gov/pubmed/35243478
http://dx.doi.org/10.1016/j.ibneur.2022.02.004

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