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m(6)A methyltransferase KIAA1429 acts as an oncogenic factor in colorectal cancer by regulating SIRT1 in an m(6)A-dependent manner

N6-methyladenosine (m6A) modifications of RNAs are involved in various aspects of colorectal carcinogenesis via regulation of mRNA stability, splicing, and translation. KIAA1429, an m6A methyltransferase, was found deregulated in multiple cancer types. However, its role in colorectal cancer remains...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Pei, Zhengda, Maimaiti, Aizezi, Zheng, Linyi, Zhu, Zhongcheng, Tian, Mengxiang, Zhou, Zhongyi, Tan, Fengbo, Pei, Qian, Li, Yuqiang, Liu, Wenxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881457/
https://www.ncbi.nlm.nih.gov/pubmed/35217651
http://dx.doi.org/10.1038/s41420-022-00878-w