Cargando…
Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
The formylpeptide receptors (FPRs) mediate pattern recognition of formylated peptides derived from invading pathogens or mitochondria from dead host cells. They can also sense other structurally distinct native peptides and even lipid mediators to either promote or resolve inflammation. Pharmacologi...
Autores principales: | Zhuang, Youwen, Wang, Lei, Guo, Jia, Sun, Dapeng, Wang, Yue, Liu, Weiyi, Xu, H. Eric, Zhang, Cheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881469/ https://www.ncbi.nlm.nih.gov/pubmed/35217703 http://dx.doi.org/10.1038/s41467-022-28586-0 |
Ejemplares similares
-
N-Formylpeptides Induce Two Distinct Concentration Optima for Mouse Neutrophil Chemotaxis by Differential Interaction with Two N-Formylpeptide Receptor (Fpr) Subtypes: Molecular Characterization of Fpr2, a Second Mouse Neutrophil Fpr
por: Hartt, Jennifer K., et al.
Publicado: (1999) -
The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells
por: Huang, J, et al.
Publicado: (2010) -
Structure of formylpeptide receptor 2-G(i) complex reveals insights into ligand recognition and signaling
por: Zhuang, Youwen, et al.
Publicado: (2020) -
The Contribution of Chemoattractant GPCRs, Formylpeptide Receptors, to Inflammation and Cancer
por: Liang, Weiwei, et al.
Publicado: (2020) -
Chemotactic Ligands that Activate G-Protein-Coupled Formylpeptide Receptors
por: Krepel, Stacey A, et al.
Publicado: (2019)