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Asparaginyl endopeptidase protects against podocyte injury in diabetic nephropathy through cleaving cofilin-1

Podocyte injury and loss are critical events in diabetic nephropathy (DN); however, the underlying molecular mechanisms remain unclear. Here, we demonstrate that asparaginyl endopeptidase (AEP) protects against podocyte injury through modulating the dynamics of the cytoskeleton. AEP was highly upreg...

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Detalles Bibliográficos
Autores principales:	Lei, Chuntao, Li, Mengran, Qiu, Yang, Xie, Yaru, Hao, Zhe, Yin, Xingjie, Zhang, Zhentao, Su, Hua, Yang, Linlin, Lin, Jihong, Hammes, Hans-Peter, Zhang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881581/ https://www.ncbi.nlm.nih.gov/pubmed/35217650 http://dx.doi.org/10.1038/s41419-022-04621-2

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