TOB1 Blocks Intestinal Mucosal Inflammation Through Inducing ID2-Mediated Suppression of Th1/Th17 Cell Immune Responses in IBD

BACKGROUND & AIMS: TOB1 is an anti-proliferative protein of Tob/BTG family and typically involved in the tumorigenesis and T cell activation. Although TOB1 is associated with T helper 17 cell–related autoimmunity, its role in modulating T cell–mediated immune responses in IBD remains poorly unde...

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Detalles Bibliográficos
Autores principales: Lin, Ritian, Ma, Caiyun, Fang, Leilei, Xu, Chunjin, Zhang, Cui, Wu, Xiaohan, Wu, Wei, Zhu, Ruixin, Cong, Yingzi, Liu, Zhanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881672/
https://www.ncbi.nlm.nih.gov/pubmed/34920145
http://dx.doi.org/10.1016/j.jcmgh.2021.12.007

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