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Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells

PIWI-interacting RNAs (piRNAs) bind to PIWI proteins to assemble the piRISC, which represses germline transposons. Maelstrom (Mael) is necessary for piRISC biogenesis in germ cells, but its function remains unclear. Here, we show that Mael interconnects Spindle-E (Spn-E), a key piRISC biogenesis fac...

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Detalles Bibliográficos
Autores principales:	Namba, Yurika, Iwasaki, Yuka W., Nishida, Kazumichi M., Nishihara, Hidenori, Sumiyoshi, Tetsutaro, Siomi, Mikiko C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881725/ https://www.ncbi.nlm.nih.gov/pubmed/35243263 http://dx.doi.org/10.1016/j.isci.2022.103914

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