RBFOX2 is required for establishing RNA regulatory networks essential for heart development

Human genetic studies identified a strong association between loss of function mutations in RBFOX2 and hypoplastic left heart syndrome (HLHS). There are currently no Rbfox2 mouse models that recapitulate HLHS. Therefore, it is still unknown how RBFOX2 as an RNA binding protein contributes to heart d...

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Detalles Bibliográficos
Autores principales: Verma, Sunil K, Deshmukh, Vaibhav, Thatcher, Kaitlyn, Belanger, KarryAnne K, Rhyner, Alexander M, Meng, Shu, Holcomb, Richard Joshua, Bressan, Michael, Martin, James F, Cooke, John P, Wythe, Joshua D, Widen, Steven G, Lincoln, Joy, Kuyumcu-Martinez, Muge N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881802/
https://www.ncbi.nlm.nih.gov/pubmed/35137168
http://dx.doi.org/10.1093/nar/gkac055

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