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Co-deficiency of B7-H3 and B7-H4 identifies high CD8 + T cell infiltration and better prognosis in pancreatic cancer

BACKGROUND: Immunotherapy is a novel hotspot for the treatment of pancreatic adenocarcinoma (PAAD). However, potential biomarkers which could identify the inflamed tumor microenvironment (TME) are urgently required. METHODS: In the present study, we measured the levels of B7-H3, B7-H4, and major tum...

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Detalles Bibliográficos
Autores principales: Si, Shuping, Wang, Lei, Cao, Hui, Xu, Yuhua, Zhan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881843/
https://www.ncbi.nlm.nih.gov/pubmed/35219310
http://dx.doi.org/10.1186/s12885-022-09294-w