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The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model

In order to understand how Wuhan curbed the COVID-19 outbreak in 2020, we build a network transmission model of 123 dimensions incorporating the impact of quarantine and medical resources as well as household transmission. Using our new model, the final infection size of Wuhan is predicted to be 50,...

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Autores principales: Feng, Shanshan, Zhang, Juping, Li, Juan, Luo, Xiao-Feng, Zhu, Huaiping, Li, Michael Y., Jin, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881901/
https://www.ncbi.nlm.nih.gov/pubmed/35218432
http://dx.doi.org/10.1007/s11538-021-00989-y
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author Feng, Shanshan
Zhang, Juping
Li, Juan
Luo, Xiao-Feng
Zhu, Huaiping
Li, Michael Y.
Jin, Zhen
author_facet Feng, Shanshan
Zhang, Juping
Li, Juan
Luo, Xiao-Feng
Zhu, Huaiping
Li, Michael Y.
Jin, Zhen
author_sort Feng, Shanshan
collection PubMed
description In order to understand how Wuhan curbed the COVID-19 outbreak in 2020, we build a network transmission model of 123 dimensions incorporating the impact of quarantine and medical resources as well as household transmission. Using our new model, the final infection size of Wuhan is predicted to be 50,662 (95%CI: 46,234, 55,493), and the epidemic would last until April 25 (95%CI: April 23, April 29), which are consistent with the actual situation. It is shown that quarantining close contacts greatly reduces the final size and shorten the epidemic duration. The opening of Fangcang shelter hospitals reduces the final size by about 17,000. Had the number of hospital beds been sufficient when the lockdown started, the number of deaths would have been reduced by at least 54.26%. We also investigate the distribution of infectious individuals in unquarantined households of different sizes. The high-risk households are those with size from two to four before the peak time, while the households with only one member have the highest risk after the peak time. Our findings provide a reference for the prevention, mitigation and control of COVID-19 in other cities of the world.
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spelling pubmed-88819012022-02-28 The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model Feng, Shanshan Zhang, Juping Li, Juan Luo, Xiao-Feng Zhu, Huaiping Li, Michael Y. Jin, Zhen Bull Math Biol Special Issue: Mathematics and Covid-19 In order to understand how Wuhan curbed the COVID-19 outbreak in 2020, we build a network transmission model of 123 dimensions incorporating the impact of quarantine and medical resources as well as household transmission. Using our new model, the final infection size of Wuhan is predicted to be 50,662 (95%CI: 46,234, 55,493), and the epidemic would last until April 25 (95%CI: April 23, April 29), which are consistent with the actual situation. It is shown that quarantining close contacts greatly reduces the final size and shorten the epidemic duration. The opening of Fangcang shelter hospitals reduces the final size by about 17,000. Had the number of hospital beds been sufficient when the lockdown started, the number of deaths would have been reduced by at least 54.26%. We also investigate the distribution of infectious individuals in unquarantined households of different sizes. The high-risk households are those with size from two to four before the peak time, while the households with only one member have the highest risk after the peak time. Our findings provide a reference for the prevention, mitigation and control of COVID-19 in other cities of the world. Springer US 2022-02-26 2022 /pmc/articles/PMC8881901/ /pubmed/35218432 http://dx.doi.org/10.1007/s11538-021-00989-y Text en © The Author(s), under exclusive licence to Society for Mathematical Biology 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Special Issue: Mathematics and Covid-19
Feng, Shanshan
Zhang, Juping
Li, Juan
Luo, Xiao-Feng
Zhu, Huaiping
Li, Michael Y.
Jin, Zhen
The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title_full The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title_fullStr The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title_full_unstemmed The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title_short The Impact of Quarantine and Medical Resources on the Control of COVID-19 in Wuhan based on a Household Model
title_sort impact of quarantine and medical resources on the control of covid-19 in wuhan based on a household model
topic Special Issue: Mathematics and Covid-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881901/
https://www.ncbi.nlm.nih.gov/pubmed/35218432
http://dx.doi.org/10.1007/s11538-021-00989-y
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