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Prediction of Tacrolimus Dose/Weight-Adjusted Trough Concentration in Pediatric Refractory Nephrotic Syndrome: A Machine Learning Approach

PURPOSE: Tacrolimus (TAC) is a first-line immunosuppressant for patients with refractory nephrotic syndrome (NS). However, there is a high inter-patient variability of TAC pharmacokinetics, thus therapeutic drug monitoring (TDM) is required. In this study, we aimed to employ machine learning algorit...

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Detalles Bibliográficos
Autores principales:	Mo, Xiaolan, Chen, Xiujuan, Wang, Xianggui, Zhong, Xiaoli, Liang, Huiying, Wei, Yuanyi, Deng, Houliang, Hu, Rong, Zhang, Tao, Chen, Yilu, Gao, Xia, Huang, Min, Li, Jiali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881964/ https://www.ncbi.nlm.nih.gov/pubmed/35228813 http://dx.doi.org/10.2147/PGPM.S339318

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