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Sex and APOE ɛ4 modify the effect of cardiovascular risk on tau in cognitively normal older adults

The interaction between APOE ɛ4 and vascular risk factors on cognitive function is stronger in women than in men. These effects may be mediated by the amount of tau pathology in the brain. Therefore, we examined whether APOE ɛ4 and sex modify cross-sectional associations between cardiovascular risk...

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Detalles Bibliográficos
Autores principales: Tsiknia, Amaryllis A., Reas, Emilie, Bangen, Katherine J., Sundermann, Erin E., McEvoy, Linda, Brewer, James B., Edland, Steven D., Banks, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882003/
https://www.ncbi.nlm.nih.gov/pubmed/35233525
http://dx.doi.org/10.1093/braincomms/fcac035