Cargando…

Downregulation of TIGIT Expression in FOXP3+Regulatory T Cells in Acute Coronary Syndrome

OBJECTIVE: Little is currently known on the role of T-cell immunoglobulin and ITIM domain (TIGIT) expression in Foxp3+ regulatory T cells (TIGIT+Tregs) in acute coronary syndrome (ACS) patients. The aim of this study was to investigate the role and alterations of TIGIT+Tregs in ACS patients. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Xinlin, Luo, Zhenhua, Zhou, Haiyan, Duan, Zonggang, Niu, Li, Zhang, Kai, Huang, Guangwei, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882028/ https://www.ncbi.nlm.nih.gov/pubmed/35228811 http://dx.doi.org/10.2147/JIR.S351364

Ejemplares similares

Correlation of apolipoprotein A‐I with T cell subsets and interferon‐ү in coronary artery disease
por: Xiong, Xinlin, et al.
Publicado: (2023)

The relationship between soluble lymphocyte activation gene-3 and coronary artery disease
por: Xiong, Xinlin, et al.
Publicado: (2022)

Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma
por: Iwasaki, Takeshi, et al.
Publicado: (2023)

Characteristic of TIGIT and DNAM-1 Expression on Foxp3+ γδ T Cells in AML Patients
por: Jin, Zhenyi, et al.
Publicado: (2020)

TIGIT in cancer immunotherapy
por: Chauvin, Joe-Marc, et al.
Publicado: (2020)

Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4(+) Treg Cells in Patients with Rheumatoid Arthritis
por: Yang, Mengru, et al.
Publicado: (2019)

TIGIT(+) iTregs elicited by human regulatory macrophages control T cell immunity
por: Riquelme, Paloma, et al.
Publicado: (2018)

Discovery of TIGIT inhibitors based on DEL and machine learning
por: Xiong, Feng, et al.
Publicado: (2022)

Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes
por: Lin, Ying-zhong, et al.
Publicado: (2013)

FOXP3 inhibits angiogenesis by downregulating VEGF in breast cancer
por: Li, Xiaoju, et al.
Publicado: (2018)

Dynamic Expressions of TIGIT on Splenic T Cells and TIGIT-Mediated Splenic T Cell Dysfunction of Mice With Chronic Toxoplasma gondii Infection
por: Li, Haoran, et al.
Publicado: (2021)

Correlation of Blood FoxP3+ Regulatory T Cells and Disease Activity of Atopic Dermatitis
por: Li, Yan, et al.
Publicado: (2019)

Rheumatoid Fibroblast-like Synoviocytes Downregulate Foxp3 Expression by Regulatory T Cells Via GITRL/GITR Interaction
por: Kim, Sung Hoon, et al.
Publicado: (2012)

Overexpression of TIGIT in NK and T Cells Contributes to Tumor Immune Escape in Myelodysplastic Syndromes
por: Meng, Fanqiao, et al.
Publicado: (2020)

Expression of TIGIT in splenic and circulatory T cells from mice acutely infected with Toxoplasma gondii
por: Wang, Shuai, et al.
Publicado: (2021)

TIGIT-based immunotherapeutics in lung cancer
por: Patel, Akshay J, et al.
Publicado: (2023)

TIGIT Can Exert Immunosuppressive Effects on CD8(+) T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro
por: Zhang, Changkun, et al.
Publicado: (2020)

DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease
por: Jacobs, Marleen E, et al.
Publicado: (2020)

UXT is a novel regulatory factor of regulatory T cells associated with Foxp3
por: Li, Weina, et al.
Publicado: (2014)

Expression of the immune checkpoint receptor TIGIT in seminoma
por: Hinsch, Andrea, et al.
Publicado: (2019)

Computer-aided design of PVR mutants with enhanced binding affinity to TIGIT
por: Zhou, Xiaowen, et al.
Publicado: (2021)

FOXP3 Inhibits the Metastasis of Breast Cancer by Downregulating the Expression of MTA1
por: Liu, Chenlin, et al.
Publicado: (2021)

TIGIT as a Promising Therapeutic Target in Autoimmune Diseases
por: Yue, Chenran, et al.
Publicado: (2022)

PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice
por: Chen, Haiming, et al.
Publicado: (2018)

Use of aspirin in the prevention of colorectal cancer through TIGIT‐CD155 pathway
por: Ma, Bin, et al.
Publicado: (2019)

Low expression and hypermethylation of FOXP3 in regulatory T cells are associated with asthma in children
por: Zhu, Xiaohua, et al.
Publicado: (2020)

Human FOXP3(+) T regulatory cell heterogeneity
por: Mohr, Audrey, et al.
Publicado: (2018)

Targeting LAG-3, TIM-3, and TIGIT for cancer immunotherapy
por: Cai, Letong, et al.
Publicado: (2023)

Functional Reprogramming of Regulatory T cells in the absence of Foxp3
por: Charbonnier, Louis-Marie, et al.
Publicado: (2019)

Mechanisms of TIGIT-driven immune suppression in cancer
por: Kurtulus, Sema, et al.
Publicado: (2014)

Update in TIGIT Immune-Checkpoint Role in Cancer
por: Annese, Tiziana, et al.
Publicado: (2022)

TIGIT in Lung Cancer: Potential Theranostic Implications
por: Pescia, Carlo, et al.
Publicado: (2023)

Transgene IL-6 Enhances DC-Stimulated CTL Responses by Counteracting CD4(+)25(+)Foxp3(+) Regulatory T Cell Suppression via IL-6-Induced Foxp3 Downregulation
por: Bhanumathy, Kalpana Kalyanasundaram, et al.
Publicado: (2014)

Corrigendum: PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice
por: Chen, Haiming, et al.
Publicado: (2020)

FOXP3+ regulatory T cells and the immune escape in solid tumours
por: Qiu, Yiran, et al.
Publicado: (2022)

Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer
por: Blessin, Niclas C., et al.
Publicado: (2019)

Expression of the immune checkpoint receptor TIGIT in Hodgkin’s lymphoma
por: Li, Wenchao, et al.
Publicado: (2018)

TIGIT-Fc as a Potential Therapeutic Agent for Fetomaternal Tolerance
por: Fu, Wenyan, et al.
Publicado: (2021)

TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis
por: Brauneck, Franziska, et al.
Publicado: (2022)

Autocrine TGF-β1 Maintains the Stability of Foxp3(+) Regulatory T Cells via IL-12Rβ2 Downregulation
por: Choi, Garam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3ndedmdhraj4sq3mqng4jfd9a5