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piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis

The pathological hallmark of the majority of amyotrophic lateral sclerosis (ALS) cases is the mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43), an RNA-binding protein. Several studies have attributed disease processes of ALS to abnormal RNA metabolism. However, dysregulated bio...

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Detalles Bibliográficos
Autores principales: Abdelhamid, Rehab F., Ogawa, Kotaro, Beck, Goichi, Ikenaka, Kensuke, Takeuchi, Eriko, Yasumizu, Yoshiaki, Jinno, Jyunki, Kimura, Yasuyoshi, Baba, Kousuke, Nagai, Yoshitaka, Okada, Yukinori, Saito, Yuko, Murayama, Shigeo, Mochizuki, Hideki, Nagano, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882100/
https://www.ncbi.nlm.nih.gov/pubmed/35015250
http://dx.doi.org/10.1007/s12035-021-02686-2

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