Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130.

Macrophages are increased in human benign prostatic hyperplasia and prostate cancer. We generate a Pb-Csf1 mouse model with prostate-specific overexpression of macrophage colony-stimulating factor (M-Csf/Csf1). Csf1 overexpression promotes immune cell infiltration into the prostate, modulates the ma...

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Detalles Bibliográficos
Autores principales: Kwon, Oh-Joon, Zhang, Boyu, Jia, Deyong, Zhang, Li, Wei, Xing, Zhou, Zhicheng, Liu, Deli, Huynh, Khoi Trung, Zhang, Kai, Zhang, Yiqun, Labhart, Paul, Sboner, Andrea, Barbieri, Chris, Haffner, Michael C, Creighton, Chad J, Xin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882147/
https://www.ncbi.nlm.nih.gov/pubmed/34999736
http://dx.doi.org/10.1038/s41388-021-02169-7

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