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Identification of Nanog as a novel inhibitor of Rad51

To develop inhibitors targeting DNA damage repair pathways is important to improve the effectiveness of chemo- and radiotherapy for cancer patients. Rad51 mediates homologous recombination (HR) repair of DNA damages. It is widely overexpressed in human cancers and overwhelms chemo- and radiotherapy-...

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Detalles Bibliográficos
Autores principales: Xin, Ying, Wang, Juanjuan, Wu, Yahong, Li, Qianqian, Dong, Mingyang, Liu, Chang, He, Qijia, Wang, Ruifeng, Wang, Dian, Jiang, Sen, Xiao, Wei, Tian, Yang, Zhang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882189/
https://www.ncbi.nlm.nih.gov/pubmed/35220392
http://dx.doi.org/10.1038/s41419-022-04644-9