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Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic

BACKGROUND: During the COVID-19 outbreak, numerous reports indicated a higher mortality rate among cardiovascular patients. We investigated how this trend applied to patients admitted to the cardiac intensive care unit (CICU). METHODS: We retrospectively compared CICU patients admitted during the in...

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Autores principales: Koren, Ofir, Shachar, Moriah, Shahar, Amit, Barbour, Mohammad, Rozner, Ehud, Benhamou, Daniel, Rosenberg, Alisa Leeds, Turgeman, Yoav, Naami, Robert, Naami, Edmund, Mader, Einat, Rajab, Saleem Abu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Southern Society for Clinical Investigation. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882251/
https://www.ncbi.nlm.nih.gov/pubmed/35235812
http://dx.doi.org/10.1016/j.amjms.2022.02.007
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author Koren, Ofir
Shachar, Moriah
Shahar, Amit
Barbour, Mohammad
Rozner, Ehud
Benhamou, Daniel
Rosenberg, Alisa Leeds
Turgeman, Yoav
Naami, Robert
Naami, Edmund
Mader, Einat
Rajab, Saleem Abu
author_facet Koren, Ofir
Shachar, Moriah
Shahar, Amit
Barbour, Mohammad
Rozner, Ehud
Benhamou, Daniel
Rosenberg, Alisa Leeds
Turgeman, Yoav
Naami, Robert
Naami, Edmund
Mader, Einat
Rajab, Saleem Abu
author_sort Koren, Ofir
collection PubMed
description BACKGROUND: During the COVID-19 outbreak, numerous reports indicated a higher mortality rate among cardiovascular patients. We investigated how this trend applied to patients admitted to the cardiac intensive care unit (CICU). METHODS: We retrospectively compared CICU patients admitted during the initial peak of the COVID outbreak between February and May 2020 (Covid Era, CE group) to a control group in pre-pandemic time in 2019. We interviewed patients to determine the symptom onset time and the time interval between symptomology and hospital arrival. RESULTS: The data of 292 patients were used in the analysis (119 patients in the CE group and 173 in the control group). CE patients had a higher incidence of ischemic heart disease (IHD) (p<.03), heart failure (p<.04), and psychiatric disorders (p<.001). During COVID time, more patients were hospitalized with myocarditis (OR: 26.45), arrhythmias (OR: 2.88), and new heart failure (HF) (p<.001) and less with STEMI (OR: 0.39; 95% CI: 0.24–0.63). Fewer PCIs were performed in the CE group (p<.001), with an overall lower success rate (p<.05) than reported in the control group. Patients in the CE group reported a longer period between symptom onset to hospital arrival (p<.001, χ2 = 12.42). The six-month survival rate was significantly lower in CE patients (χ2 = 7.01, P = 0.008). CONCLUSIONS: Among CICU patients admitted to our center during the initial period of the COVID pandemic, STEMI events were less frequent while cases of newly diagnosed HF sharply increased. Patients waited longer after symptom onset before seeking medical care during the pandemic. The delay may have resulted in clinical deterioration that could explain the high mortality rate and the new HF admission rate.
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spelling pubmed-88822512022-02-28 Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic Koren, Ofir Shachar, Moriah Shahar, Amit Barbour, Mohammad Rozner, Ehud Benhamou, Daniel Rosenberg, Alisa Leeds Turgeman, Yoav Naami, Robert Naami, Edmund Mader, Einat Rajab, Saleem Abu Am J Med Sci Clinical Investigation BACKGROUND: During the COVID-19 outbreak, numerous reports indicated a higher mortality rate among cardiovascular patients. We investigated how this trend applied to patients admitted to the cardiac intensive care unit (CICU). METHODS: We retrospectively compared CICU patients admitted during the initial peak of the COVID outbreak between February and May 2020 (Covid Era, CE group) to a control group in pre-pandemic time in 2019. We interviewed patients to determine the symptom onset time and the time interval between symptomology and hospital arrival. RESULTS: The data of 292 patients were used in the analysis (119 patients in the CE group and 173 in the control group). CE patients had a higher incidence of ischemic heart disease (IHD) (p<.03), heart failure (p<.04), and psychiatric disorders (p<.001). During COVID time, more patients were hospitalized with myocarditis (OR: 26.45), arrhythmias (OR: 2.88), and new heart failure (HF) (p<.001) and less with STEMI (OR: 0.39; 95% CI: 0.24–0.63). Fewer PCIs were performed in the CE group (p<.001), with an overall lower success rate (p<.05) than reported in the control group. Patients in the CE group reported a longer period between symptom onset to hospital arrival (p<.001, χ2 = 12.42). The six-month survival rate was significantly lower in CE patients (χ2 = 7.01, P = 0.008). CONCLUSIONS: Among CICU patients admitted to our center during the initial period of the COVID pandemic, STEMI events were less frequent while cases of newly diagnosed HF sharply increased. Patients waited longer after symptom onset before seeking medical care during the pandemic. The delay may have resulted in clinical deterioration that could explain the high mortality rate and the new HF admission rate. Southern Society for Clinical Investigation. Published by Elsevier Inc. 2022-08 2022-02-27 /pmc/articles/PMC8882251/ /pubmed/35235812 http://dx.doi.org/10.1016/j.amjms.2022.02.007 Text en © 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Clinical Investigation
Koren, Ofir
Shachar, Moriah
Shahar, Amit
Barbour, Mohammad
Rozner, Ehud
Benhamou, Daniel
Rosenberg, Alisa Leeds
Turgeman, Yoav
Naami, Robert
Naami, Edmund
Mader, Einat
Rajab, Saleem Abu
Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title_full Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title_fullStr Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title_full_unstemmed Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title_short Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic
title_sort profile trends of non-covid patients admitted to the cardiac intensive care unit during the 2020 covid pandemic
topic Clinical Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882251/
https://www.ncbi.nlm.nih.gov/pubmed/35235812
http://dx.doi.org/10.1016/j.amjms.2022.02.007
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