Single-cell transcriptomic profiling unravels the adenoma-initiation role of protein tyrosine kinases during colorectal tumorigenesis

The adenoma-carcinoma sequence is a well-accepted roadmap for the development of sporadic colorectal cancer. However, cellular heterogeneity in aberrant epithelial cells limits our understanding of carcinogenesis in colorectal tissues. Here, we performed a single-cell RNA sequencing survey of 54,788...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaobo, Song, Jinen, Yu, Chune, Zhou, Zongguang, Liu, Xiaowei, Yu, Jing, Xu, Guangchao, Yang, Jiqiao, He, Xiujing, Bai, Xin, Luo, Ya, Bao, Yu, Li, Huifang, Yang, Lie, Xu, Mingqing, Song, Nan, Su, Xiaodong, Xu, Jie, Ma, Xuelei, Shi, Hubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882672/
https://www.ncbi.nlm.nih.gov/pubmed/35221332
http://dx.doi.org/10.1038/s41392-022-00881-8

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