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Gene deletion of γ‐actin impairs insulin‐stimulated skeletal muscle glucose uptake in growing mice but not in mature adult mice

The cortical cytoskeleton, consisting of the cytoplasmic actin isoforms β and/or γ‐actin, has been implicated in insulin‐stimulated GLUT4 translocation and glucose uptake in muscle and adipose cell culture. Furthermore, transgenic inhibition of multiple actin‐regulating proteins in muscle inhibits i...

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Detalles Bibliográficos
Autores principales: Knudsen, Jonas R., Madsen, Agnete B., Li, Zhencheng, Andersen, Nicoline R., Schjerling, Peter, Jensen, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882697/
https://www.ncbi.nlm.nih.gov/pubmed/35224890
http://dx.doi.org/10.14814/phy2.15183

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