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Gene deletion of γ‐actin impairs insulin‐stimulated skeletal muscle glucose uptake in growing mice but not in mature adult mice
The cortical cytoskeleton, consisting of the cytoplasmic actin isoforms β and/or γ‐actin, has been implicated in insulin‐stimulated GLUT4 translocation and glucose uptake in muscle and adipose cell culture. Furthermore, transgenic inhibition of multiple actin‐regulating proteins in muscle inhibits i...
Autores principales: | Knudsen, Jonas R., Madsen, Agnete B., Li, Zhencheng, Andersen, Nicoline R., Schjerling, Peter, Jensen, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882697/ https://www.ncbi.nlm.nih.gov/pubmed/35224890 http://dx.doi.org/10.14814/phy2.15183 |
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