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Gasdermin-E Mediated Pyroptosis—A Novel Mechanism Regulating Migration, Invasion and Release of Inflammatory Cytokines in Rheumatoid Arthritis Fibroblast-like Synoviocytes

Synovium fibroblast-like synoviocytes (FLSs) are important participants in the pathogenesis of synovitis and joint destruction in rheumatoid arthritis (RA). Pyroptosis is a pro-inflammatory and cell lytic programmed cell death mechanism mediated by gasdermin (GSDM) family proteins. In this study, we...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Zhang, Xue-Pei, Zhang, Qian, Zou, Yao-Yao, Ma, Jian-Da, Chen, Le-Feng, Zou, Yao-Wei, Xue, Ji-Meng, Ma, Ruo-Fan, Chen, Zhong, Dai, Lie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882760/
https://www.ncbi.nlm.nih.gov/pubmed/35237610
http://dx.doi.org/10.3389/fcell.2021.810635