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Blood Glutamate Scavenging With Pyruvate as a Novel Preventative and Therapeutic Approach for Depressive-Like Behavior Following Traumatic Brain Injury in a Rat Model
Depression is a common and serious complication following traumatic brain injury (TBI). Both depression and TBI have independently been associated with pathologically elevated extracellular brain glutamate levels. In the setting of TBI, blood glutamate scavenging with pyruvate has been widely shown...
Autores principales: | Frank, Dmitry, Gruenbaum, Benjamin F., Shelef, Ilan, Zvenigorodsky, Vladislav, Severynovska, Olena, Gal, Ron, Dubilet, Michael, Zlotnik, Alexander, Kofman, Ora, Boyko, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883046/ https://www.ncbi.nlm.nih.gov/pubmed/35237125 http://dx.doi.org/10.3389/fnins.2022.832478 |
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