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Impact of immune-related adverse events on the therapeutic efficacy of pembrolizumab in urothelial carcinoma: a multicenter retrospective study using time-dependent analysis
BACKGROUND: Several studies have reported the incidence of immune-related adverse events (irAEs) as a predictor of the efficacy of anti-programmed cell death protein 1 antibodies in patients with cancer. However, immortal time bias has not always been fully addressed in these studies. In this retros...
Autores principales: | Kawai, Taketo, Taguchi, Satoru, Nakagawa, Tohru, Kamei, Jun, Nakamura, Yu, Obinata, Daisuke, Yamaguchi, Kenya, Kaneko, Tomoyuki, Kakutani, Shigenori, Tokunaga, Mayuko, Uemura, Yukari, Sato, Yusuke, Enomoto, Yutaka, Nishimatsu, Hiroaki, Fujimura, Tetsuya, Fukuhara, Hiroshi, Takahashi, Satoru, Kume, Haruki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883255/ https://www.ncbi.nlm.nih.gov/pubmed/35210308 http://dx.doi.org/10.1136/jitc-2021-003965 |
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