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Bedtime versus morning use of antihypertensives for cardiovascular risk reduction (BedMed): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial

INTRODUCTION: Sleep-time blood pressure correlates more strongly with adverse cardiovascular events than does daytime blood pressure. The BedMed trial evaluates whether bedtime antihypertensive administration, as compared with conventional morning use, reduces major adverse cardiovascular events. ME...

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Detalles Bibliográficos
Autores principales: Garrison, Scott R, Kolber, Michael R, Allan, G Michael, Bakal, Jeffrey, Green, Lee, Singer, Alexander, Trueman, Darryl R, McAlister, Finlay A, Padwal, Raj S, Hill, Michael D, Manns, Braden, McGrail, Kimberlyn, O'Neill, Braden, Greiver, Michelle, Froentjes, Liesbeth S, Manca, Donna P, Mangin, Dee, Wong, Sabrina T, MacLean, Cathy, Kirkwood, Jessica EM, McCracken, Rita, McCormack, James P, Norris, Colleen, Korownyk, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883279/
https://www.ncbi.nlm.nih.gov/pubmed/35210352
http://dx.doi.org/10.1136/bmjopen-2021-059711