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Bedtime versus morning use of antihypertensives for cardiovascular risk reduction (BedMed): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial
INTRODUCTION: Sleep-time blood pressure correlates more strongly with adverse cardiovascular events than does daytime blood pressure. The BedMed trial evaluates whether bedtime antihypertensive administration, as compared with conventional morning use, reduces major adverse cardiovascular events. ME...
Autores principales: | Garrison, Scott R, Kolber, Michael R, Allan, G Michael, Bakal, Jeffrey, Green, Lee, Singer, Alexander, Trueman, Darryl R, McAlister, Finlay A, Padwal, Raj S, Hill, Michael D, Manns, Braden, McGrail, Kimberlyn, O'Neill, Braden, Greiver, Michelle, Froentjes, Liesbeth S, Manca, Donna P, Mangin, Dee, Wong, Sabrina T, MacLean, Cathy, Kirkwood, Jessica EM, McCracken, Rita, McCormack, James P, Norris, Colleen, Korownyk, Tina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883279/ https://www.ncbi.nlm.nih.gov/pubmed/35210352 http://dx.doi.org/10.1136/bmjopen-2021-059711 |
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