Cargando…
Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging
Efficient proteostasis is crucial for somatic maintenance, and its decline during aging leads to cellular dysfunction and disease. Selective autophagy is a form of autophagy mediated by receptors that target specific cargoes for degradation and is an essential process to maintain proteostasis. The p...
Autores principales: | Kumar, Anita V., Mills, Joslyn, Lapierre, Louis R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883344/ https://www.ncbi.nlm.nih.gov/pubmed/35237597 http://dx.doi.org/10.3389/fcell.2022.793328 |
Ejemplares similares
-
Non-canonical autophagy in aging and age-related diseases
por: Kumar, Anita V., et al.
Publicado: (2023) -
CUL5–ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy
por: Gong, Liyan, et al.
Publicado: (2021) -
The Autophagy Regulator p62 Controls PTEN-Dependent Ciliogenesis
por: Mun, Hyowon, et al.
Publicado: (2020) -
ATM Kinase-Dependent Regulation of Autophagy: A Key Player in Senescence?
por: Stagni, Venturina, et al.
Publicado: (2021) -
BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62
por: Friesen, Erik L., et al.
Publicado: (2020)