Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides

Background: Glycyrrhizic acid (GA) has been reported to be liver protective; however, the characters and underlying mechanisms of GA against tripterygium glycoside tablet (TGT)-induced acute liver injury remain unelucidated. Hypothesis/Purpose: We assumed that GA could relieve TGT-induced acute live...

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Detalles Bibliográficos
Autores principales: Shi, Qiaoli, Wang, Qixin, Chen, Jiayun, Xia, Fei, Qiu, Chong, Li, Min, Zhao, Minghong, Zhang, Qian, Luo, Piao, Lu, Tianming, Zhang, Ying, Xu, Liting, He, Xueling, Zhong, Tianyu, Lin, Na, Guo, Qiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883433/
https://www.ncbi.nlm.nih.gov/pubmed/35237151
http://dx.doi.org/10.3389/fphar.2021.822154

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